2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

PDF 2.67 MB

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N12538
    trans-Cinnamic anhydride
    		Inhibitor
    trans-Cinnamic anhydride is a Parasite inhibitor tnat can be isolated from Cinnamomum zeylanicum and exhibits moderate activity against Plasmodium falciparum.
    trans-Cinnamic anhydride
  • HY-106338
    Polyketomycin
    		Inhibitor
    Polyketomycin is a tetracyclic quinone glycoside antibiotic isolated from Streptomyces sp. or Streptomyces diastatochromogenes. Polyketomycin inhibits growth of Gram-positive bacteria, and its MIC values is less than 0.2 µg/mL. Polyketomycin has antibacterial, anticancer, antimalarial activities.
    Polyketomycin
  • HY-136440R
    Hydroxymetronidazole (Standard)
    		Inhibitor
    Hydroxymetronidazole (Standard) is the analytical standard of Hydroxymetronidazole. This product is intended for research and analytical applications. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle.
    Hydroxymetronidazole (Standard)
  • HY-W675573
    VF-149
    		Inhibitor
    VF-149 is a Ribonucleotide reductase inhibitor. VF-149 significantly inhibits Plasmodium falciparum growth with an IC50 of 6.4  μM. VF-149 has antimalarial and antitumor activities. VF-149 can be used for malarial infections and cancers research.
    VF-149
  • HY-N7173
    7-Methoxy-β-carboline-1-propionic acid
    		Inhibitor
    7-Methoxy-β-carboline-1-propionic acid (compound 46) is a cytotoxic and antimalarial compound. 7-Methoxy-β-carboline-1-propionic acid can be extracted from the roots of Eurycoma longifolia.
    7-Methoxy-β-carboline-1-propionic acid
  • HY-112542A
    Nemadectin (90%)
    		Inhibitor
    Nemadectin (90%) (CL-287088 (90%)), an orally active broad-spectrum endectocide and macrolide antibiotic. Nemadectin shows anthelmintic activity against T. canis, A. caninum and U. stenocephala.
    Nemadectin (90%)
  • HY-179451
    Apoptosis inducer 53
    		Inhibitor
    Apoptosis inducer 53 is an apoptosis inducer. Apoptosis inducer 53 can inhibit proliferation of human tumor cell lines (A549, HeLa, SW1573, T-47D, WiDr) with GI50 values of 2.5-9.1 μM. Apoptosis inducer 53 can induce cancer cells apoptosis and reduce colony formation. Apoptosis inducer 53 can activate p38α MAPK signaling and exerts anti-inflammatory effect. Apoptosis inducer 53 also shows anti-Leishmania donovani activity. Apoptosis inducer 53 can be used for the researches of cancer, infection and inflammation.
    Apoptosis inducer 53
  • HY-N3156
    Odoratone
    		Inhibitor
    Odoratone (Dehydroodoratol) has insecticidal activity (LC50: 154 ppm).
    Odoratone
  • HY-151943
    Antitrypanosomal agent 11
    		Inhibitor
    Antitrypanosomal agent 11 is an antitrypanosomal agent that inhibits Trypanosoma cruzi with an IC50 of 0.23 μM.
    Antitrypanosomal agent 11
  • HY-158335
    DXR-IN-1
    		Inhibitor
    DXR-IN-1 (Compound 13E) is an inhibitor of 1-deoxy-D-ketose 5-phosphate reductoisomerase (DXR). DXR-IN-1 is highly selective for P. falciparum DXR (IC50=0.030 μM). DXR-IN-1 inhibits the growth of P. falciparum by binding to the active site of DXR and blocking its catalytic activity.
    DXR-IN-1
  • HY-146649
    LmCPB-IN-1
    		Inhibitor
    LmCPB-IN-1 (compound 35) is a potent and reversible covalent Leishmania mexicana cysteine protease B (LmCPB) inhibitor with a pKi of 9.7.
    LmCPB-IN-1
  • HY-165440
    Cyclobenzaprine
    		Inhibitor
    Cyclobenzaprine (MK130) is an orally active 5-HT2 receptor antagonist. Cyclobenzaprine acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Cyclobenzaprine also possesses antiparasitic activity. Cyclobenzaprine holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases.
    Cyclobenzaprine
  • HY-161170
    Antimalarial agent 36
    		Inhibitor
    Antimalarial agent 36 (compound 1) is an antimalarial agent, with the EC50s of 58 nM and 42 nM, for Dd2 and 3D7, respectively. Antimalarial agent 36 targets EphA2.
    Antimalarial agent 36
  • HY-U00045
    Epsiprantel
    		Inhibitor
    Epsiprantel (BRL-38705) is a compound with anti-Echinococcus activity that can cause the death of protoscolex, larvae and adults in vitro, and is more effective against mature worms than larvae in vivo, with no side effects.
    Epsiprantel
  • HY-N9746
    (R)-4-Methoxydalbergione
    		Inhibitor
    (R)-4-Methoxydalbergione is a urease inhibitor with IC50s of 59.72 and 67.33 μM for Bacillus pasteurii urease and Jack bean urease. (R)-4-Methoxydalbergione also has antiplasmodial activity. (R)-4-Methoxydalbergione can be isolated from Ranunculus repens.
    (R)-4-Methoxydalbergione
  • HY-B1282R
    Sulfaquinoxaline (Standard)
    		Inhibitor
    Sulfaquinoxaline (Standard) is the analytical standard of Sulfaquinoxaline. This product is intended for research and analytical applications. Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections.
    Sulfaquinoxaline (Standard)
  • HY-N3497
    Isochamaejasmin
    		Inhibitor
    Isochamaejasmin is a biflavonoid with anti-cancer, antiplasmodial and insecticidal activities. Isochamaejasmin displays a potent NF-κB (NF-κB) activation activity. Isochamaejasmin could cause DNA damage and induce apoptosis via the mitochondrial pathway in AW1 cells. Isochamaejasmin also has a moderate antiplasmodial activity (IC50 of 7.3 μM for P. falciparum) and relatively low cytotoxicity (CC50 of 29.0 μM).
    Isochamaejasmin
  • HY-B0777R
    Moxidectin (Standard)
    		Inhibitor
    Moxidectin (Standard) is the analytical standard of Moxidectin. This product is intended for research and analytical applications. Moxidectin (CL301423) is an orally active macrolide (ML) anthelmintic for the prevention and control of heartworms and roundworms. Moxidectin is also a substrate of BCRP and P-glycoprotein (P-gp) in vivo, and is secreted into breast milk and effluxed from the host and parasite mediated by Bcrp1 and P-gp. This may be related to the presence of chemical residues in milk.
    Moxidectin (Standard)
  • HY-B1221S
    Flufenamic acid-d4
    		Inhibitor
    Flufenamic acid-d4 is deuterium labeled Flufenamic acid. Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.
    Flufenamic acid-d<sub>4</sub>
  • HY-P10390
    Insecticidal agent 11
    		Inhibitor
    Insecticidal agent 11 (compound Q6) is a potent insect growth regulator (IGR)-based insecticide. Insecticidal agent 11 shows high insecticidal activity against Diploptera punctata by inhibiting juvenile hormone (JH) biosynthesis. Insecticidal agent 11 also exhibits insecticidal activity against Plutella xylostella.
    Insecticidal agent 11
Parasite Isoform Comparison

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.